Chris Aiken, M.D.  Psychiatry & Psychotherapy

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Stimulants for ADHD

What are the benefits of stimulants?

For many people with ADHD, stimulants dramatically improve their ability to focus at work, school and in their social life. Symptoms that benefit include distractibility, short attention span, hyperactivity, mood swings, and impulsivity. The medication may also improve physical coordination, such as handwriting and ability in sports.

Are there non-stimulant options?

Atomoxetine (Strattera) is a non-stimulant medicine that appears to work as well as stimulants for most people. Other medications can be helpful, including antidepressants such as buproprion (wellbutrin), but they are generally not as effective for ADHD as stimulants.

When should I see improvement?

Improvement in symptoms should be noticeable within a few hours after taking a stimulant. If no change is seen after a week, the medicine may need to be adjusted. After symptoms improve, people with ADHD often find more benefits through changes they are now able to make in their lives.

How should I take the medicine?

Dosing will depend on how long its action lasts – see below for available options. The duration can be improved (by about an hour) and the onset made smoother if it is taken with food (30 min before a meal).

      Some people only take stimulants on work or school days, while others find the benefits extend into their leisure and social lives and take them every day; either way is equally safe.

What if I miss a dose?

You may take the dose late or wait for your next scheduled dose. Your decision will depend on how long the medicine affects you (see chart), what activities you face that day, and the possibility of sleep disruption if the dose is taken too late.

What side effects are possible?

Side effects include difficulty sleeping, nervousness, appetite loss, dizziness, upset stomach, and headache. Taking too much of the medicine can cause fear and agitation. People with Tourette’s disorder may have more tics.

      We can work together to find a dose that works with the least side effects. If insomnia occurs, try taking the last dose before 6pm. If your appetite is lowered, you can avoid weight loss by taking the medicine with food and continuing to eat snacks and full meals.

Are stimulant medicines addictive?

When taken as prescribed to treat the symptoms of ADHD, stimulants are not addictive. People with ADHD rarely abuse stimulants, and in fact treatment lowers their rates of substance abuse. However, misuse of stimulants can lead to abuse and addiction.

Will I need stimulants for life?

Symptoms of ADHD may improve as you age, and trials without medication can be attempted to see if it is still necessary. If taken as prescribed, stimulants can be safely stopped at any time.

What types of stimulants are available?

There are three main types of stimulants: ritalin (or methylphenidate), adderall, and dexedrine.  These three medicines come in several forms which differ in how slowly they are released in the stomach and how long they last (see below).  Although each form often has a different brand name (e.g. concerta, metadate), the medicine inside is the same. (An exception is Focalin which is an isomer of methylphenidate. Each molecule comes in mirror image forms – right and left.  In Focalin, only the more active form is used).

 

Methylphenidate Compounds

Name

Reaches its peak in (hours):

Effects last for (hours):

Sizes (mg)

Methylphenidate

 

1-2

3-5

Tablets: 5, 10, 20

Brands: Ritalin, Methylin chews

Methylphenidate SR

4-5

4-8

Tablets by brand:

Generic 20, Ritalin SR 20, Methylin ER 10, 20.

Metadate ER 20.

Ritalin LA

2, 5.5 (2 peaks)

8-12

Capsule: 20, 30, 40

Concerta

6-8

12

Capsule: 18, 27, 36, 54

Metadate CD

1.5, 4.5 (2 peaks)

8

Capsule: 20

Focalin (an isomer, or chemical variant, called dexmethyl-phenidate)

1-2

3-5

Tablet: 2.5, 5, 10

 

Dextroamphetamine and Amphetamine Mixture

Name

Reaches its peak in (hours):

Effects last for (hours):

Sizes (mg)

Adderall

3

4-6

Tablets: 5, 7.5, 10*, 12.5, 15, 20*, 30* (*scored tabs).

Adderall XR

7

8-12

Capsules: 5, 10, 15, 20, 25, 30

 

Dextroamphetamine

Name

Reaches its peak in (hours):

Effects last for (hours):

Sizes (mg)

Dextroamphetamine

3

10-14

Tablets: 5, 10

Brand: Dexedrine

Dextroamphetamine SR

8

10-14

Capsules: 5, 10, 15

Brand: Dexedrine Spansule

 

What else should I know?

To learn specific information about side effects, drug-interactions, pregnancy, and effects on medical problems, go to Index of Drug Information and look up your stimulant by name. 

 

Resources for ADHD

 

 

Books:

Driven to Distraction by E.M. Hallowell & J. Ratey. (1994).  Also Answers to Distraction by same author.

Attention Deficit Disorder in Adults by L. Weiss & K. Bonnet. (1997)

Out of the Fog: Treatment Options and Coping Strategies for Adult Attention Deficit Disorder by K.R. Murphy & S. LeVert. (1995).

You mean I’m not lazy, stupid or crazy?!: A Self-help Book for Adults with Attention Deficit Disorder, by K. Kelly & P. Ramundo.  (1996).

 

Internet sites:

www.chadd.org/fs/fs7.htm

www.nimh.nih.gov/publicat/adhd.cfm

www.psych.org/public_info/adhdfactsheet42401.pdf

 

Organizations:

CHADD (Children and Adults w/ ADHD)
8181 Professional Place, Suite 201
Landover, MD 20785
(301) 306-7070, (800) 233-4050
www.chadd.org, email national@chadd.org

National Attention Deficit Disorder Association
1788 Second Street, Suite 200
Highland Park, IL 60035
(847) 432-2332
www.add.org, email: mail@add.org

Updated 9/21/4 by Chris Aiken, M.D.